Antiphospholipid Antibodies and Systemic Scleroderma

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Antiphospholipid Antibodies and Systemic Scleroderma

OBJECTIVE Antiphospholipid antibodies (APLs) could be associated with an increased risk of vascular pathologies in systemic scleroderma. The aim of our study was to search for APLs in patients affected by systemic scleroderma and to evaluate their involvement in the clinical manifestations of this disease. MATERIALS AND METHODS We conducted a cross-sectional descriptive study, from January 20...

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Antiphospholipid Antibodies and Systemic Scleroderma

Dear Editor: We read with great interest the article by Touré and colleagues published in a recent issue of your journal, entitled " Antiphospholipid Antibodies and Systemic Scleroderma ". In this study, they investigated 40 patients with systemic scleroderma (SSc) for the presence of antiphospholipid antibodies (aPLs). Overall, they found aPLs in 23 (57.5%) patients. The most frequently encoun...

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Antiphospholipid antibodies in systemic lupus erythematosus and the antiphospholipid syndrome.

The family of autoantibodies known as antiphospholipid antibodies (aPL) and the lupus anticoagulant (LA) are associated with a spectrum of clinical manifestations including life-threatening thrombosis. While our current knowledge of thrombosis is imperfect and the mere presence of aPL is imprecisely associated with clinical events, our knowledge in this area has greatly expanded in recent years...

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Anti-beta2glycoprotein I (anti-beta2GPI) antibodies constitute the main autoantibody specificity in the sera of patients with antiphospholipid syndrome (APS). There is evidence that anti-beta2GPI antibodies induce the precoagulant activity of the endothelium by cross-linking the beta2 glycoprotein I (beta2GPI) on the cell surface. Since beta2GPI lacks intracellular domains, homology with other ...

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Antiphospholipid antibodies, systemic lupus erythematosus, and non-traumatic metatarsal fractures.

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ژورنال

عنوان ژورنال: Turkish Journal of Hematology

سال: 2013

ISSN: 1300-7777

DOI: 10.4274/tjh.2012.0059